Pomegranate, known for its bright red seeds and refreshing taste, is more than just a flavorful fruit. For centuries, it has been valued in traditional medicine for its healing properties. In recent years, growing awareness about heart health has brought pomegranate juice into the spotlight, with many claiming it can clear blocked arteries and even reverse early atherosclerosis.

But how much of this belief is supported by scientific evidence? Here’s what research really says about pomegranate juice and cardiovascular health.
What Science Says About Pomegranate Juice
Several studies have explored the effects of pomegranate on arterial health, with some promising findings.
An NIH-supported study published in Clinical Nutrition followed patients with carotid artery stenosis (narrowing of arteries in the neck) over a three-year period. Participants who consumed pomegranate juice daily experienced a reduction in arterial thickness along with lower systolic blood pressure. Notably, these benefits appeared early and continued throughout the study duration.
Another study published in the journal Atherosclerosis found that pomegranate extract helped reduce markers of arterial inflammation. Since chronic inflammation plays a major role in the progression of heart disease, researchers suggested that pomegranate may help protect coronary arteries.
However, experts caution that not all studies show consistent or dramatic reductions in arterial plaque. Much of the existing research involves small sample sizes, and evidence directly proving plaque reversal remains limited.
How Pomegranate Juice Supports Artery Health Indirectly
While pomegranate juice is not a standalone cure for blocked arteries, research highlights several indirect benefits that contribute to cardiovascular wellness.
1. Powerful Antioxidant Protection
Pomegranate is rich in polyphenols, especially punicalagins, which have strong antioxidant properties. These compounds help reduce oxidative stress on arterial walls, potentially slowing plaque formation and supporting healthier blood vessels.
2. Anti-Inflammatory Effects
Chronic inflammation accelerates arterial damage and plaque buildup. Studies show that pomegranate extract can lower inflammatory markers, which may help stabilize existing plaques and reduce the risk of heart-related complications.
3. Support for Healthy Cholesterol
NIH research suggests that pomegranate compounds may prevent the oxidation of LDL (bad) cholesterol, a crucial step in plaque development. While it may not significantly lower cholesterol levels alone, reducing LDL oxidation supports long-term arterial health.
4. Blood Pressure Regulation
Regular consumption of pomegranate juice has been linked to lower systolic blood pressure. Reduced blood pressure means less strain on artery walls, indirectly lowering the risk of cardiovascular damage.
The Bottom Line
Pomegranate juice does not directly clear blocked arteries or reverse atherosclerosis on its own. However, scientific evidence suggests it can play a supportive role in heart health by reducing inflammation, oxidative stress, LDL oxidation, and blood pressure.
When combined with a balanced diet, regular exercise, and medical guidance, pomegranate juice can be a valuable addition to a heart-healthy lifestyle — but it should not be viewed as a magic cure.
